Abstract: A method for simultaneous determination of major and minor components including MgO, Al2O3, SiO2, P, S, CaO, TiO2, V2O5, Mn and Fe in titanium concentrate samples by Xray fluorescence spectrometry was introduced. The calibration standards were prepared by mixing high pure titanium dioxide and iron ore standards. The flux selection, fusion conditions, positioning of V Kα line and matrix effects were also studied. The results from the standard sample analysis are in agreement with the certified values with the precision of less than 5% RSD (n=7) except P and S (at low content). This method fully satisfies the requirements of titanium concentrate analysis.