Abstract: Advances in Inorganic Geochemistry have often been dependant on introduction of new technology. The development of Inductively Coupled Plasma Mass Spectrometry (ICPMS) has allowed high-precision isotopic analysis of elements previously very difficult to analyse. In Oxford we have invested heavily in Multiple Collector Plasma Mass Spectrometry to address problems ranging from Cosmic to Environmental Chemistry. Examples of current projects being pursued are an investigation of Cr-isotopes to identify a possible impact event at the Jurassic-Triassic boundary, and the use of U-series isotopes in Oceanography.