【引用本文】 曹孝文, 邹宽, 徐丹, 等. 食品中有机氯农药和多氯联苯气相色谱-质谱分析的离子化方式[J]. 岩矿测试, 2013, 32(1): 22-27.
CAO Xiao-wen, ZOU Kuan, XU Dan, et al. Different Ionization Modes in Gas Chromatography-Mass Spectrometric Determination of Organochlorine Pesticides and Polychlorinated Biphenyls in Food[J]. Rock and Mineral Analysis, 2013, 32(1): 22-27.

食品中有机氯农药和多氯联苯气相色谱-质谱分析的离子化方式

1. 

生命分析化学国家重点实验室,南京大学化学化工学院,南京大学现代分析中心,江苏 南京 210093

2. 

江苏出入境检验检疫局,江苏 南京 210001

收稿日期: 2012-05-24  接受日期: 2012-06-09

基金项目: 国家重点基础研究发展计划(973计划)项目(2009CB421601); 国家自然科学基金项目(90913012);公益性行业科研专项基金项目(200810099)

作者简介: 曹孝文,硕士,从事食品安全分析。E-mail:cherrycxw@126.com。

通信作者: 练鸿振,博士,教授,博士生导师,主要从事色谱/质谱分析研究。E-mail:hzlian@nju.edu.cn 葛欣,博士,教授,主要从事色谱/质谱分析研究。E-mail:gexin@nju.edu.cn

Different Ionization Modes in Gas Chromatography-Mass Spectrometric Determination of Organochlorine Pesticides and Polychlorinated Biphenyls in Food

1. 

State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry & Chemical Engineering and Center of Materials Analysis, Nanjing University, Nanjing 210093, China

2. 

Jiangsu Entry-Exit Inspection and Quarantine Bureau, Nanjing 210001, China

Corresponding author: LIAN Hong-zhen, hzlian@nju.edu.cnCorresponding author: GE Xin, gexin@nju.edu.cn

Received Date: 2012-05-24
Accepted Date: 2012-06-09

摘要:对食品中有机氯农药和多氯联苯的气相色谱-质谱联用(GC-MS)分析方法中三种离子化方式,电子轰击电离(EI)、正化学电离(PCI)和负化学电离(NCI)进行了总结和比较。PCI-MS/MS方法和EI-MS/MS方法都有很高的选择性和较高的灵敏度;PCI方法在分析含硝基、羰基等基团的化合物时有明显优势,EI则在分析狄氏剂、异狄氏剂、硫丹及其代谢物时比PCI表现稍好,而NCI-MS的灵敏度最高,但抗干扰能力稍弱,且不适合分析滴滴涕类和多氯联苯类化合物。在食品安全分析中,三种质谱方法的准确性好,精密度高,检测限较低,都能够满足食品中农残检测的要求,在日常检测工作中可互为补充和替代。同时指出,GC在有机氯化合物分析中仍表现出明显的优越性;常规的GC-MS尤其在EI电离模式下,易受到基质干扰而使谱图变得复杂;新型离子化方式包括高选择性化学电离技术的应用,将是食品安全中GC-MS联用分析的发展方向之一。

关键词: 食品, 有机氯农药, 多氯联苯, 气相色谱-质谱法, 离子化方式

Different Ionization Modes in Gas Chromatography-Mass Spectrometric Determination of Organochlorine Pesticides and Polychlorinated Biphenyls in Food

KEY WORDS: food, organochlorine pesticides, polychlorinated biphenyls, Gas Chromatography-Mass Spectrometry, ionization mode

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食品中有机氯农药和多氯联苯气相色谱-质谱分析的离子化方式

曹孝文, 邹宽, 徐丹, 沈伟健, 练鸿振, 葛欣, 沈崇钰