【引用本文】 宋淑玲, 田芹, 佟玲, 等. 生物样品母乳中有机氯农药类化合物近二十年研究进展[J]. 岩矿测试, 2016, 35(5): 449-457. doi: 10.15898/j.cnki.11-2131/td.2016.05.002
SONG Shu-ling, TIAN Qin, TONG Ling, et al. Research Progress of Organochlorine Pesticides in Breast Milk of Biological Samples in the Last Twenty Years[J]. Rock and Mineral Analysis, 2016, 35(5): 449-457. doi: 10.15898/j.cnki.11-2131/td.2016.05.002

生物样品母乳中有机氯农药类化合物近二十年研究进展

1. 

国家地质实验测试中心, 北京 100037

2. 

中国地质科学院地球物理地球化学勘查研究所, 河北 廊坊 065000

收稿日期: 2016-03-27  修回日期: 2016-06-01  接受日期: 2016-09-09

基金项目: 国家自然科学基金面上项目(41473008);国家自然科学基金青年基金项目(21307018);中国地质科学院基本科研业务费项目(YWF201402)

作者简介: 宋淑玲, 博士研究生, 副研究员, 主要从事环境中有机污染物分析方法和暴露评价方法研究。E-mail:songshuling163@163.com。

Research Progress of Organochlorine Pesticides in Breast Milk of Biological Samples in the Last Twenty Years

1. 

National Research Center for Geoanalysis, Beijing 100037, China

2. 

Institute of Geophysical and Geochemical Exploration, Chinese Academy of Geological Sciences, Langfang 065000, China

Received Date: 2016-03-27
Revised Date: 2016-06-01
Accepted Date: 2016-09-09

摘要:有机氯农药(OCPs)至今是人体内残留浓度和检出率最高的有机污染物,母乳作为一种生物介质,被广泛用于人体中OCPs蓄积量、母乳中OCPs浓度的影响因素、婴幼儿母乳喂养期OCPs摄入量、人体中OCPs排泄动力学等研究领域。近二十年的研究表明:母乳中残留的OCPs主要有六氯苯(HCB)、滴滴涕(DDTs)和六六六(HCHs),浓度持续下降,总体上发展中国家高于发达国家,沿海地区高于内陆地区,热带地区高于其他地区;母乳中OCPs浓度主要受饮食习惯、年龄和分娩次数等因素的影响,在哺乳期浓度并不是持续下降,其排泄速度呈波动性变化趋势;不同国家和地区婴幼儿母乳喂养时OCPs日摄入量普遍低于WHO/FAO建议值,但在一些仍然使用OCPs的热带地区,婴幼儿OCPs日摄入量比WHO/FAO建议值高出几十倍。未来有关母乳中OCPs的研究将主要集中于:继续开展母乳中OCPs方法学研究,推进分析方法的标准化,提高评价方法和统计学方法的应用范围和可靠性;研究高暴露区和污染区OCPs对婴幼儿早期发育和未来生长健康的影响;研究OCPs在人体内的蓄积和排泄规律;结合统计学方法,开展母乳中OCPs与新生儿或成年人各种疾病相关性的统计流行病学研究。

关键词: 生物样品, 母乳, 持久性有机污染物, 有机氯农药, 婴幼儿

Research Progress of Organochlorine Pesticides in Breast Milk of Biological Samples in the Last Twenty Years

KEY WORDS: biological sample, breast milk, persistent organic pollutants, organochlorine pesticides, inflant

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生物样品母乳中有机氯农药类化合物近二十年研究进展

宋淑玲, 田芹, 佟玲, 潘萌, 马生明